Single-nucleus transcriptome profiling provides insights into the pathophysiology of OSA-related renal injury

Abstract Obstructive sleep apnea (OSA) has been demonstrated to be associated with renal injury. However, the cellular and molecular mechanisms by which chronic intermittent hypoxia (CIH), a hallmark of OSA, contributes to renal injury remain poorly understood. Twelve male Sprague-Dawley rats were r...

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Podrobná bibliografie

Hlavní autoři:	Ya-Ping Huang, Zhi-Wei Huang, Yu-Zhen Huang, Xiao-Bin Zhang, Jing Song, Wen-Sen Huang, Yi-Na Huang, Li Lin, Li-Da Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-10-01
Edice:	Scientific Reports
Témata:	Obstructive sleep apnea Chronic intermittent hypoxia Renal injury Single-nucleus RNA sequencing
On-line přístup:	https://doi.org/10.1038/s41598-025-23736-y
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