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Single-nucleus transcriptome profiling provides insights into the pathophysiology of OSA-related renal injury

Abstract Obstructive sleep apnea (OSA) has been demonstrated to be associated with renal injury. However, the cellular and molecular mechanisms by which chronic intermittent hypoxia (CIH), a hallmark of OSA, contributes to renal injury remain poorly understood. Twelve male Sprague-Dawley rats were r...

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Autores principales: Ya-Ping Huang, Zhi-Wei Huang, Yu-Zhen Huang, Xiao-Bin Zhang, Jing Song, Wen-Sen Huang, Yi-Na Huang, Li Lin, Li-Da Chen
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2025-10-01
Colección:Scientific Reports
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Acceso en línea:https://doi.org/10.1038/s41598-025-23736-y
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