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Improving the suppressive power of homing gene drive by co-targeting a distant-site female fertility gene

Abstract Gene drive technology has the potential to address major biological challenges. Well-studied homing suppression drives have been shown to be highly efficient in Anopheles mosquitoes, but for other organisms, lower rates of drive conversion prevent elimination of the target population. To ta...

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Bibliografische gegevens
Hoofdauteurs: Nicky R. Faber, Xuejiao Xu, Jingheng Chen, Shibo Hou, Jie Du, Bart A. Pannebakker, Bas J. Zwaan, Joost van den Heuvel, Jackson Champer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2024-10-01
Reeks:Nature Communications
Online toegang:https://doi.org/10.1038/s41467-024-53631-5
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