A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma

Abstract Cancers evolve not only through the acquisition and clonal transmission of somatic mutations but also by epigenetic mechanisms that modify cell phenotype. Here, we use histology-guided and spatial transcriptomics to characterize hepatoblastoma, a childhood liver cancer that exhibits signifi...

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書誌詳細

主要な著者:	Peng V. Wu, Matt Fish, Florette K. Hazard, Chunfang Zhu, Sujay Vennam, Hannah Walton, Dhananjay Wagh, John Coller, Joanna Przybyl, Maurizio Morri, Norma Neff, Robert B. West, Roel Nusse
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2024-11-01
シリーズ:	Nature Communications
オンライン･アクセス:	https://doi.org/10.1038/s41467-024-53802-4
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