Evidence of Adult Features and Functions of Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells and Self-Organized as Organoids

Background: Human-induced pluripotent stem cell-derived hepatocytes (iHeps) have been shown to have considerable potential in liver diseases, toxicity, and pharmacological studies. However, there is a growing need to obtain iHeps that are truly similar to primary adult hepatocytes in terms of morpho...

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Detalhes bibliográficos

Principais autores:	Antonietta Messina, Eléanor Luce, Nassima Benzoubir, Mattia Pasqua, Ulysse Pereira, Lydie Humbert, Thibaut Eguether, Dominique Rainteau, Jean-Charles Duclos-Vallée, Cécile Legallais, Anne Dubart-Kupperschmitt
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-02-01
coleção:	Cells
Assuntos:	liver organoids hiPSCs hiPSC-derived hepatocytes HLCs self-assembling hepatic mature functions
Acesso em linha:	https://www.mdpi.com/2073-4409/11/3/537
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