Evidence of Adult Features and Functions of Hepatocytes Differentiated from Human Induced Pluripotent Stem Cells and Self-Organized as Organoids

Background: Human-induced pluripotent stem cell-derived hepatocytes (iHeps) have been shown to have considerable potential in liver diseases, toxicity, and pharmacological studies. However, there is a growing need to obtain iHeps that are truly similar to primary adult hepatocytes in terms of morpho...

Descripció completa

Dades bibliogràfiques

Autors principals:	Antonietta Messina, Eléanor Luce, Nassima Benzoubir, Mattia Pasqua, Ulysse Pereira, Lydie Humbert, Thibaut Eguether, Dominique Rainteau, Jean-Charles Duclos-Vallée, Cécile Legallais, Anne Dubart-Kupperschmitt
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-02-01
Col·lecció:	Cells
Matèries:	liver organoids hiPSCs hiPSC-derived hepatocytes HLCs self-assembling hepatic mature functions
Accés en línia:	https://www.mdpi.com/2073-4409/11/3/537
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!