Luciferase reporter mycobacteriophage (TM4::GeNL) enables rapid assessment of drug susceptibilities and inducible macrolide resistance in Mycobacterium abscessus complex

ABSTRACT Mycobacterium abscessus (MAB) infections are challenging to treat due to high-level resistance to anti-tuberculosis drugs, carbapenems, fluoroquinolones, and tetracyclines. Clarithromycin and amikacin are considered cornerstone drugs for MAB treatment due to their superior efficacy; however...

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Detalhes bibliográficos

Principais autores:	Saranathan Rajagopalan, Lahari Das, Donna J. Kohlerschmidt, Amy K. Rourke, Salika M. Shakir, Michelle H. Larsen, Max R. O’Donnell, Wendy A. Szymczak, Vincent E. Escuyer, Phyu M. Thwe, William R. Jacobs
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2025-09-01
coleção:	Journal of Clinical Microbiology
Assuntos:	Mycobacterium abscessus inducible macrolide resistance amikacin luciferase reporter mycobacteriophage erm(41)
Acesso em linha:	https://journals.asm.org/doi/10.1128/jcm.00841-25
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