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Luciferase reporter mycobacteriophage (TM4::GeNL) enables rapid assessment of drug susceptibilities and inducible macrolide resistance in Mycobacterium abscessus complex

ABSTRACT Mycobacterium abscessus (MAB) infections are challenging to treat due to high-level resistance to anti-tuberculosis drugs, carbapenems, fluoroquinolones, and tetracyclines. Clarithromycin and amikacin are considered cornerstone drugs for MAB treatment due to their superior efficacy; however...

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主要な著者: Saranathan Rajagopalan, Lahari Das, Donna J. Kohlerschmidt, Amy K. Rourke, Salika M. Shakir, Michelle H. Larsen, Max R. O’Donnell, Wendy A. Szymczak, Vincent E. Escuyer, Phyu M. Thwe, William R. Jacobs
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2025-09-01
シリーズ:Journal of Clinical Microbiology
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オンライン・アクセス:https://journals.asm.org/doi/10.1128/jcm.00841-25
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