HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein
<p>Abstract</p> <p>Background</p> <p>The discovery of diketoacid-containing derivatives as inhibitors of HIV-1 Integrase (IN) (IN inhibitors, IINs) has played a major role in validating this enzyme as an important target for antiretroviral therapy. Since the <it>in vivo </it>efficacy depends on acce...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2007-03-01
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| Seria: | Retrovirology |
| Dostęp online: | http://www.retrovirology.com/content/4/1/17 |
| Etykiety: |
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