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Clorfl86/RHEX Is a Negative Regulator of SCF/KIT Signaling in Human Skin Mast Cells

Mast cells (MCs) are key effector cells in allergic and inflammatory diseases, and the SCF/KIT axis regulates most aspects of the cells’ biology. Using terminally differentiated skin MCs, we recently reported on proteome-wide phosphorylation changes initiated by KIT dimerization. C1orf186/RHEX was r...

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Principais autores: Kristin Franke, Gürkan Bal, Zhuoran Li, Torsten Zuberbier, Magda Babina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-05-01
coleção:Cells
Assuntos:
mast cell
RHEX
C1orf186
survival
apoptosis
signal transduction
Acesso em linha:https://www.mdpi.com/2073-4409/12/9/1306
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