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Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism

Abstract TMEM106B is an endolysosomal transmembrane protein not only associated with multiple neurological disorders including frontotemporal dementia, Alzheimer’s disease, and hypomyelinating leukodystrophy but also potentially involved in COVID-19. Additionally, recent studies have identified amyl...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hideyuki Takahashi, Azucena Perez-Canamas, Chris W. Lee, Hongping Ye, Xianlin Han, Stephen M. Strittmatter
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2024-09-01
Cyfres:Communications Biology
Mynediad Ar-lein:https://doi.org/10.1038/s42003-024-06810-5
Tagiau: Ychwanegu Tag
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