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Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism

Abstract TMEM106B is an endolysosomal transmembrane protein not only associated with multiple neurological disorders including frontotemporal dementia, Alzheimer’s disease, and hypomyelinating leukodystrophy but also potentially involved in COVID-19. Additionally, recent studies have identified amyl...

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Bibliografski detalji
Glavni autori: Hideyuki Takahashi, Azucena Perez-Canamas, Chris W. Lee, Hongping Ye, Xianlin Han, Stephen M. Strittmatter
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2024-09-01
Serija:Communications Biology
Online pristup:https://doi.org/10.1038/s42003-024-06810-5
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