USP8 promotes the tumorigenesis of intrahepatic cholangiocarcinoma via stabilizing OGT
Abstract Ubiquitination was considered to be a crucial factor in intrahepatic cholangiocarcinoma (iCCA) development. Herein, we identified Ubiquitin-specific peptidase 8 (USP8) as a key regulator for promoting the tumorigenesis of iCCA cell via stabilizing OGT. USP8 was overexpressed in human tumor...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2024-07-01
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| Serie: | Cancer Cell International |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s12935-024-03370-w |
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