USP8 promotes the tumorigenesis of intrahepatic cholangiocarcinoma via stabilizing OGT
Abstract Ubiquitination was considered to be a crucial factor in intrahepatic cholangiocarcinoma (iCCA) development. Herein, we identified Ubiquitin-specific peptidase 8 (USP8) as a key regulator for promoting the tumorigenesis of iCCA cell via stabilizing OGT. USP8 was overexpressed in human tumor...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2024-07-01
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| Series: | Cancer Cell International |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s12935-024-03370-w |
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