A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases
How G-quadruplexes (G4s) are resolved by helicases is still a matter of investigation. Here the authors provide mechanistic insight into G4s unwinding by presenting a crystal structure of resolved G4 DNA and the G4 binding domain of RecQ helicase from the bacterium Cronobacter sakazakii.
Gardado en:
| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2018-10-01
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| Series: | Nature Communications |
| Acceso en liña: | https://doi.org/10.1038/s41467-018-06751-8 |
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