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Porcine Reproductive and Respiratory Syndrome Virus NSP8 Suppresses NF-κB Signaling by Hijacking Host UBE2K and IKKα

The Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) has evolved sophisticated immune-evasion strategies to establish a productive infection in the host, primarily by counteracting the innate antiviral response. Here, we demonstrate for the first time that the PRRSV non-structural protein...

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Principais autores: Da Liu, Yan Yan, Xuezhen Fu, Linglong Qin, Jiayu Ma, Hui Zhou, Shiping Sun, Haimin Li, Weiren Dong, Jiyong Zhou
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-05-01
Serier:Viruses
Fag:
UBE2K
PRRSV
NSP8
IKKα
NF-κB
ubiquitination
Online adgang:https://www.mdpi.com/1999-4915/18/5/567
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