Klotho Protects Dopaminergic Neuron Oxidant-Induced Degeneration by Modulating ASK1 and p38 MAPK Signaling Pathways.

Klotho transgenic mice exhibit resistance to oxidative stress as measured by their urinal levels of 8-hydroxy-2-deoxyguanosine, albeit this anti-oxidant defense mechanism has not been locally investigated in the brain. Here, we tested the hypothesis that the reactive oxygen species (ROS)-sensitive a...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Reynolds K Brobey, Dwight German, Patricia K Sonsalla, Prem Gurnani, Johanne Pastor, C-C Hsieh, John Papaconstantinou, Philip P Foster, Makoto Kuro-o, Kevin P Rosenblatt
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Public Library of Science (PLoS) 2015-01-01
Sarja:	PLoS ONE
Linkit:	https://doi.org/10.1371/journal.pone.0139914
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