Farnesoid X receptor mediates macrophage-intrinsic responses to suppress colitis-induced colon cancer progression

Bile acids (BAs) affect the intestinal environment by ensuring barrier integrity, maintaining microbiota balance, regulating epithelium turnover, and modulating the immune system. As a master regulator of BA homeostasis, farnesoid X receptor (FXR) is severely compromised in patients with inflammator...

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Detalhes bibliográficos

Principais autores:	Xingchen Dong, Ming Qi, Chunmiao Cai, Yu Zhu, Yuwenbin Li, Sally Coulter, Fei Sun, Christopher Liddle, Nataliya V. Uboha, Richard Halberg, Wei Xu, Paul Marker, Ting Fu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical investigation 2024-01-01
coleção:	JCI Insight
Assuntos:	Endocrinology Gastroenterology
Acesso em linha:	https://doi.org/10.1172/jci.insight.170428
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