Follistatin supplementation induces changes in CDX2 CpG methylation and improves in vitro development of bovine SCNT preimplantation embryos

Abstract Caudal Type Homeobox 2 (CDX2) is a key regulator of trophectoderm formation and maintenance in preimplantation embryos. We previously demonstrated that supplementation of exogenous follistatin, during in vitro culture of bovine IVF embryos, upregulates CDX2 expression, possibly, via alterat...

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主要な著者:	Mohamed Ashry, Chunyan Yang, Sandeep K. Rajput, Joseph K. Folger, Jason G. Knott, George W. Smith
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2021-09-01
シリーズ:	Reproductive Biology and Endocrinology
主題:	Bovine preimplantation embryos SCNT CDX2 DNA methylation Follistatin
オンライン･アクセス:	https://doi.org/10.1186/s12958-021-00829-7
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