MDC-Analyzer: A novel degenerate primer design tool for the construction of intelligent mutagenesis libraries with contiguous sites

Recent computational and bioinformatics advances have enabled the efficient creation of novel biocatalysts by reducing amino acid variability at hot spot regions. To further expand the utility of this strategy, we present here a tool called Multi-site Degenerate Codon Analyzer (MDC-Analyzer) for the...

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Detalhes bibliográficos

Principais autores:	Lixia Tang, Xiong Wang, Beibei Ru, Hengfei Sun, Jian Huang, Hui Gao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2014-06-01
coleção:	BioTechniques
Assuntos:	partial randomization intelligent library design contiguous sites data-driven protein engineering
Acesso em linha:	https://www.future-science.com/doi/10.2144/000114177
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