An exploratory in silico comparison of open-source codon harmonization tools

Abstract Background Not changing the native constitution of genes prior to their expression by a heterologous host can affect the amount of proteins synthesized as well as their folding, hampering their activity and even cell viability. Over the past decades, several strategies have been developed t...

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Bibliografski detalji

Glavni autori:	Thomas Willems, Wim Hectors, Jeltien Rombaut, Anne-Sofie De Rop, Stijn Goegebeur, Tom Delmulle, Maarten L. De Mol, Sofie L. De Maeseneire, Wim K. Soetaert
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2023-11-01
Serija:	Microbial Cell Factories
Teme:	Synthetic Biology Codon usage Bias Codon Harmonization EuGene Galaxy CodonWizard
Online pristup:	https://doi.org/10.1186/s12934-023-02230-y
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