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Impaired glymphatic clearance is an important cause of Alzheimer’s disease

Alzheimer’s disease (AD) is the leading cause of dementia worldwide. The disease is characterized by the abnormal accumulation of amyloid β (Aβ) protein creating neuritic plaques, hyperphosphorylated tau (p-tau) protein forming intracellular tangles, and neuronal degeneration. Pathological changes r...

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Principais autores: Iyawnna Hazzard, Maryann Batiste, Tianyu Luo, Cyrus Cheung, Forshing Lui
Format: Artigo
Sprog:Inglês
Udgivet: Open Exploration Publishing Inc. 2024-10-01
Serier:Exploration of Neuroprotective Therapy
Fag:
alzheimer’s disease
glymphatic system
amyloid β accumulation
hyperphosphorylated tau protein
neurofibrillary tangles
aquaporin-4
Online adgang:https://www.explorationpub.com/Journals/ent/Article/100491
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