Targeting the glymphatic system to promote α-synuclein clearance: a novel therapeutic strategy for Parkinson’s disease

The excessive buildup of neurotoxic α-synuclein plays a pivotal role in the pathogenesis of Parkinson’s disease, highlighting the urgent need for innovative therapeutic strategies to promote α-synuclein clearance, particularly given the current lack of disease-modifying treatments. The glymphatic sy...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Xiaoyue Lian, Zhenghao Liu, Zuobin Gan, Qingshan Yan, Luyao Tong, Linan Qiu, Yuntao Liu, Jiang-fan Chen, Zhihui Li
Format:	Artigo
Jezik:	Inglês
Izdano:	Wolters Kluwer Medknow Publications 2026-01-01
Serija:	Neural Regeneration Research
Teme:	aquaporin-4 astrocytes cerebrospinal fluid glymphatic system interstitial fluid neurotoxic protein clearance parkinson’s disease perivascular spaces sleep disturbance α-synuclein
Online dostop:	https://journals.lww.com/10.4103/NRR.NRR-D-24-00764
Oznake:	Označite Brez oznak, prvi označite!