Management of diarrhoea in patients with stable ulcerative colitis with low FODMAP diet, amitriptyline, ondansetron or loperamide: the MODULATE RCT

Background Many patients with ulcerative colitis report ongoing diarrhoea even when their disease is stable and in remission. Design MODULATE was a pragmatic, multicentre, seamless, adaptive, phase 2/3 open-label, parallel-group, multiarm multistage randomised controlled trial. Setting and participa...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Lauren A Moreau, Alexander Charles Ford, Matthew James Brookes, Sandra Graca, Elspeth Guthrie, Suzanne Hartley, Lesley Houghton, Karen Kemp, Nicholas A Kennedy, Yvonne McKenzie, Delia Muir, Pei Loo Ow, Christopher Probert, Emma Pryde, Christopher Taylor, Thomas A Willis, Alexandra Wright-Hughes, Amanda J Farrin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	NIHR Journals Library 2025-03-01
coleção:	Health Technology Assessment
Assuntos:	ulcerative colitis randomised controlled trial multiarm multistage platform trial decentralised trial
Acesso em linha:	https://doi.org/10.3310/GHFE4871
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!