Effect of TAR hairpin stabilization on HIV-1 reverse transcription

ABSTRACT Reverse transcription of the human immunodeficiency virus type 1 (HIV-1) genome requires the first strand transfer that relies on a base-pairing interaction between the 3′ R sequence of the genomic RNA (gRNA) and the r sequence of the strong-stop DNA (ssDNA). The annealing reaction between...

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主要な著者:	Sandra Da Silva Amaral, Clémence Richetta, Lola Oualid, Nhat Quang Tu, Brigitte René, Olivier Mauffret, Olivier Delelis, Philippe Fossé
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology 2026-05-01
シリーズ:	Journal of Virology
主題:	HIV-1 reverse transcription TAR strand transfer nucleocapsid protein structure
オンライン･アクセス:	https://journals.asm.org/doi/10.1128/jvi.01840-25
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