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Suppressing PD-L1 Expression via AURKA Kinase Inhibition Enhances Natural Killer Cell-Mediated Cytotoxicity against Glioblastoma

Immunotherapies have shown significant promise as an impactful strategy in cancer treatment. However, in glioblastoma multiforme (GBM), the most prevalent primary brain tumor in adults, these therapies have demonstrated lower efficacy than initially anticipated. Consequently, there is an urgent need...

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Hlavní autoři: Trang T. T. Nguyen, Qiuqiang Gao, Jeong-Yeon Mun, Zhe Zhu, Chang Shu, Aaron Naim, Meri Rogava, Benjamin Izar, Mike-Andrew Westhoff, Georg Karpel-Massler, Markus D. Siegelin
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2024-07-01
Edice:Cells
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On-line přístup:https://www.mdpi.com/2073-4409/13/13/1155
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