Structural basis of frizzled 7 activation and allosteric regulation
Abstract Frizzleds (ten paralogs: FZD1-10) belong to the class F of G protein-coupled receptors (GPCRs), which remains poorly understood despite its crucial role in multiple key biological functions including embryonic development, stem cell regulation, and homeostasis in the adult. FZD7, one of the...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Portfolio
2024-08-01
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| Serija: | Nature Communications |
| Online pristup: | https://doi.org/10.1038/s41467-024-51664-4 |
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