Platinum(IV)-Loaded Degraded Glycol Chitosan as Efficient Platinum(IV) Drug Delivery Platform

A new class of anticancer prodrugs was designed by combining the cytotoxicity of platinum(IV) complexes and the drug carrier properties of glycol chitosan polymers: Unsymmetrically carboxylated platinum(IV) analogues of cisplatin, carboplatin and oxaliplatin, namely (OC-6-44)-acetatodiammine(3-carbo...

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Huvudupphov:	Yvonne Lerchbammer-Kreith, Nadine S. Sommerfeld, Klaudia Cseh, Xian Weng-Jiang, Uchechukwu Odunze, Andreas G. Schätzlein, Ijeoma F. Uchegbu, Mathea S. Galanski, Michael A. Jakupec, Bernhard K. Keppler
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2023-03-01
Serie:	Pharmaceutics
Ämnen:	platinum(IV) complexes glycol chitosan anticancer drug delivery
Länkar:	https://www.mdpi.com/1999-4923/15/4/1050
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