Dysregulated biosynthesis and hydrolysis of cyclic-di-adenosine monophosphate impedes sporulation and butanol and acetone production in Clostridium beijerinckii NCIMB 8052

IntroductionAlthough solventogenic Clostridium species (SCS) produce butanol, achieving high enough titers to warrant commercialization of biobutanol remains elusive. Thus, deepening our understanding of the intricate cellular wiring of SCS is crucial to unearthing new targets and strategies for eng...

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Principais autores:	Marian M. Awaga-Cromwell, Santosh Kumar, Hieu M. Truong, Eric Agyeman-Duah, Christopher C. Okonkwo, Victor C. Ujor
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-02-01
coleção:	Frontiers in Bioengineering and Biotechnology
Assuntos:	cyclic-di-adenosine monophosphate butanol sporulation solventogenic clostridia DNA integrity scanning protein A phosphodiesterase
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbioe.2025.1547226/full
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