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Betulinic Acid Inhibits the Stemness of Gastric Cancer Cells by Regulating the GRP78-TGF-β1 Signaling Pathway and Macrophage Polarization

Cancer stemness is the process by which cancer cells acquire chemoresistance and self-renewal in the tumor microenvironment. Glucose-regulated protein 78 (GRP78) is a biomarker for gastric cancer and is involved in cancer stemness. By inducing cancer stemness in various types of cancer, the polariza...

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Tallennettuna:
Päätekijät: Jen-Lung Chen, Yun-Shen Tai, Hsin-Yi Tsai, Chia-Yuan Hsieh, Chun-Lin Chen, Chung-Jung Liu, Deng-Chyang Wu, Yaw-Bin Huang, Ming-Wei Lin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2023-02-01
Sarja:Molecules
Aiheet:
betulinic acid
stemness
gastric cancer
GRP78
TGF-β
macrophage polarization
Linkit:https://www.mdpi.com/1420-3049/28/4/1725
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