Côd QR

Physiological Roles of the Autoantibodies to the 78-Kilodalton Glucose-Regulated Protein (GRP78) in Cancer and Autoimmune Diseases

The 78 kDa glucose-regulated protein (GRP78), a member of the 70 kDa heat-shock family of molecular chaperones (HSP70), is essential for the regulation of the unfolded protein response (UPR) resulting from cellular endoplasmic reticulum (ER) stress. During ER stress, GRP78 evades retention mechanism...

Disgrifiad llawn

Wedi'i Gadw mewn:
Prif Awduron: Mario Gonzalez-Gronow, Salvatore Vincent Pizzo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2022-05-01
Cyfres:Biomedicines
Pynciau:
cancer
autoimmune diseases
ER dysfunctions
GRP78 autoantigenicity
GRP78 cell surface compartments
GRP78 citrullination
Mynediad Ar-lein:https://www.mdpi.com/2227-9059/10/6/1222
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg