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Reduced vagal tone in women with the FMR1 premutation is associated with FMR1 mRNA but not depression or anxiety

Abstract Background Autonomic dysfunction is implicated in a range of psychological conditions, including depression and anxiety. The fragile X mental retardation-1 (FMR1) premutation is a common genetic mutation that affects ~1:150 women and is associated with psychological vulnerability. This stud...

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Principais autores: Jessica Klusek, Giuseppe LaFauci, Tatyana Adayev, W. Ted Brown, Flora Tassone, Jane E. Roberts
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-05-01
coleção:Journal of Neurodevelopmental Disorders
Assuntos:
Fragile X carriers
Vagal tone
Heart rate
Physiological arousal
FMRP
FMR1 mRNA
Acesso em linha:http://link.springer.com/article/10.1186/s11689-017-9197-6
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