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Activation Ratio Correlates with IQ in Female Carriers of the <i>FMR1</i> Premutation

Carriers of the <i>FMR1</i> premutation (PM) allele are at risk of one or more clinical conditions referred to as FX premutation-associated conditions (FXPAC). Since the <i>FMR1</i> gene is on the X chromosome, the activation ratio (AR) may impact the risk, age of onset, progression, and severity of...

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Principais autores: Dragana Protic, Roberta Polli, Ye Hyun Hwang, Guadalupe Mendoza, Randi Hagerman, Blythe Durbin-Johnson, Bruce E. Hayward, Karen Usdin, Alessandra Murgia, Flora Tassone
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-06-01
Series:Cells
Assuntos:
<i>FMR1</i> mRNA
CGG
premutation carriers
activation ratio
IQ
depression
Acceso en liña:https://www.mdpi.com/2073-4409/12/13/1711
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