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The critical role of Th17 cells and IL-17A in autoimmune and inflammation-associated neurological diseases: mechanisms and therapeutic perspectives

Helper T cells 17 (Th17) and their effector cytokine, interleukin-17A (IL-17A), play a dual role in immune homeostasis. On one hand, they are essential in defense against extracellular pathogens, such as bacteria and fungi, by inducing chemokine production and recruiting neutrophils. On the other ha...

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Bibliografiske detaljer
Principais autores: Inmaculada Xu Lou, Huifen Zhou, Haitong Wan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-11-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1656422/full
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