Caspase-1 interdomain linker cleavage is required for pyroptosis
The related human NLRP1 and CARD8 form ASC-dependent and ASC-independent inflammasomes, respectively, both of which require pro-caspase-1 interdomain linker processing for the induction of pyroptosis. Pathogen-related signals induce a number of cytosolic pattern-recognition receptors (PRRs) to form...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Life Science Alliance LLC
2020-03-01
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| Series: | Life Science Alliance |
| Acceso en liña: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202000664 |
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