The Paradoxical Role of Pyroptosis in Gastrointestinal Cancers: From Molecular Mechanisms to Therapeutic Horizons

Pyroptosis, a gasdermin-mediated and highly immunogenic form of regulated cell death, has surfaced as a critical determinant in the progression and therapeutic landscape of gastrointestinal (GI) cancers. Unlike non-inflammatory apoptotic pathways, pyroptosis involves the assembly of inflammasome com...

Ausführliche Beschreibung

Bibliografische Detailangaben

1. Verfasser:	John K. Triantafillidis
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-04-01
Schriftenreihe:	Biomedicines
Schlagworte:	pyroptosis inflammasome gasdermin gastrointestinal cancer tumor microenvironment immunotherapy
Online-Zugang:	https://www.mdpi.com/2227-9059/14/4/911
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