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Mycoplasma hyorhinis‐encoded cytidine deaminase efficiently inactivates cytosine‐based anticancer drugs

Mycoplasmas may colonize tumor tissue in patients. The cytostatic activity of gemcitabine was dramatically decreased inMycoplasma hyorhinis‐infected tumor cell cultures compared with non‐infected tumor cell cultures. This mycoplasma‐driven drug deamination could be prevented by exogenous administrat...

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Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Johan Vande Voorde, Peter Vervaeke, Sandra Liekens, Jan Balzarini
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Wiley 2015-01-01
Sraith:FEBS Open Bio
Ábhair:
Rochtain ar líne:https://doi.org/10.1016/j.fob.2015.07.007
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