Mycoplasma hyorhinis‐encoded cytidine deaminase efficiently inactivates cytosine‐based anticancer drugs
Mycoplasmas may colonize tumor tissue in patients. The cytostatic activity of gemcitabine was dramatically decreased inMycoplasma hyorhinis‐infected tumor cell cultures compared with non‐infected tumor cell cultures. This mycoplasma‐driven drug deamination could be prevented by exogenous administrat...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Wiley
2015-01-01
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| Schriftenreihe: | FEBS Open Bio |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1016/j.fob.2015.07.007 |
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