Defective pgsA contributes to increased membrane fluidity and cell wall thickening in Staphylococcus aureus with high-level daptomycin resistance

ABSTRACT Daptomycin is a membrane-targeting last-resort antimicrobial therapeutic for the treatment of infections caused by methicillin- and/or vancomycin-resistant Staphylococcus aureus. In the rare event of failed daptomycin therapy, the source of resistance is often attributable to mutations dire...

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Egile Nagusiak:	Christian D. Freeman, Tayte Hansen, Ramona Urbauer, Brian J. Wilkinson, Vineet K. Singh, Kelly M. Hines
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology 2024-06-01
Saila:	mSphere
Gaiak:	daptomycin Staphylococcus aureus pgsA yycG mprF lipidomics
Sarrera elektronikoa:	https://journals.asm.org/doi/10.1128/msphere.00115-24
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