Lola-I is a promoter pioneer factor that establishes de novo Pol II pausing during development
Abstract While the accessibility of enhancers is dynamically regulated during development, promoters tend to be constitutively accessible and poised for activation by paused Pol II. By studying Lola-I, a Drosophila zinc finger transcription factor, we show here that the promoter state can also be su...
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| Principais autores: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Portfolio
2023-09-01
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| 叢編: | Nature Communications |
| 在線閱讀: | https://doi.org/10.1038/s41467-023-41408-1 |
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