Synthesis, anticancer evaluation, and electrochemical investigation of new chiral pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides

Abstract Pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulfonamides (MM-compounds) represent a novel class of heterocyclic compounds with promising anticancer potential. In this study, we report the synthesis and biological evaluation of two enantiomeric derivatives: the R-enantiomer (MM124) and th...

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Autores principales:	Mateusz Kciuk, Gabriela Machura, Somdutt Mujwar, Beata Marciniak, Kamila Koszelska, Sylwia Smarzewska, Mariusz Mojzych, Renata Kontek
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-05-01
Colección:	Scientific Reports
Materias:	Cancer Drug Pyrazole Tetrazole Triazine
Acceso en línea:	https://doi.org/10.1038/s41598-025-02835-w
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