The Distinct Electrophysiological Mechanisms in the Cortico-Striatal Circuit of LID Rats

Levodopa-induced dyskinesia (LID) is a severe motor complication associated with long-term levodopa (L-DOPA) treatment for Parkinson’s disease (PD). Its underlying mechanisms remain unclear, and candidate biomarkers lack consistency. To investigate cortico-striatal network alterations associated wit...

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Principais autores:	Tingting He, Hongyu Wang, Haoqi Ni, Yuting Sun, Xiang Gao, Fan Zhou, Jianmin Zhang, Kedi Xu
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2026-07-01
Series:	Biology
Assuntos:	levodopa-induced dyskinesia single-neuron spikes local field potentials the dorsolateral striatum the primary motor cortex phase-amplitude coupling
Acceso en liña:	https://www.mdpi.com/2079-7737/15/13/1074
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