Enhancing striatal acetylcholine facilitates dopamine release and striatal output in parkinsonian mice

Abstract Background L-DOPA has been considered the first-line therapy for treating Parkinson’s disease (PD) via restoring striatal dopamine (DA) to normalize the activity of local spiny projection neurons (SPNs) in the direct (dSPNs) pathway and the indirect (iSPNs) pathway. While the changes in str...

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Bibliografski detalji

Glavni autori:	Hongxia Li, Ziluo Chen, Yuyan Tan, Huoqing Luo, Chen Lu, Chao Gao, Xin Shen, Fang Cai, Ji Hu, Shengdi Chen
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2024-12-01
Serija:	Cell & Bioscience
Teme:	Acetylcholine Dopamine Striatum Parkinson’s disease In vivo
Online pristup:	https://doi.org/10.1186/s13578-024-01328-z
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