Hypoxia causes trophoblast cell ferroptosis to induce miscarriage through lnc-HZ06/HIF1α-SUMO/NCOA4 axis

Defects of human trophoblast cells may induce miscarriage (abnormal early embryo loss), which is generally regulated by lncRNAs. Ferroptosis is a newly identified iron-dependent programmed cell death. Hypoxia is an important and unavoidable feature in mammalian cells. However, whether hypoxia might...

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Autori principali:	Peng Tian, Zhongyan Xu, Jiarong Guo, Jingsong Zhao, Weina Chen, Wenxin Huang, Manli Wang, Chenyang Mi, Ying Zhang, Yang Yang, Huidong Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-04-01
Serie:	Redox Biology
Soggetti:	LncRNA or lnc-HZ06 Trophoblast cell ferroptosis Hypoxia Recurrent miscarriage SUMOylated HIF1α and NCOA4
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2213231724000491
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