Development of novel pyrimidine-thio-triazoles targeting EGFR in breast Cancer cells via one-pot copper-catalyzed 1,3-dipolar cycloaddition

Background: Heterocycles are vital in medicinal chemistry due to their diverse pharmacological activities against various diseases. The development of innovative synthetic methods for heterocycles is ongoing, aiming to explore their full therapeutic potential. The epidermal growth factor receptor (E...

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Principais autores:	Bhanuprakash C. Narasimhachar, Akshay Ravish, Narasimha M. Beeraka, Baburajeev Chumadathil Pookunoth, Shreeja Basappa, Divakar Vishwanath, Kanchugarakoppal S. Rangappa, Omantheswara Nagaraja, Mahendra Madegowda, Paduvalahippe Gowdegowda Chandrashekara, Basappa Basappa
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2025-03-01
Serija:	Results in Chemistry
Teme:	Arylamine Triazole Pyrimidine Piperazine Benzimidazole
Online dostop:	http://www.sciencedirect.com/science/article/pii/S221171562500133X
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