Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells

DNAJC15 is a mitochondrial TIMM23-related co-chaperonin known for its role in regulating oxidative phosphorylation efficiency, oxidative stress response and lipid metabolism. Recently, it has been proposed that the loss of DNAJC15 correlates with cisplatin (CDDP)-resistance onset in ovarian cancer (...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Stefano Miglietta, Manuela Sollazzo, Iacopo Gherardi, Sara Milioni, Beatrice Cavina, Lorena Marchio, Monica De Luise, Camelia Alexandra Coada, Marco Fiorillo, Anna Myriam Perrone, Ivana Kurelac, Giuseppe Gasparre, Luisa Iommarini, Anna Maria Ghelli, Anna Maria Porcelli
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	The Royal Society 2025-01-01
Serie:	Open Biology
Soggetti:	DNAJC15 ovarian cancer cisplatin resistance ferroptosis mitochondria
Accesso online:	https://royalsocietypublishing.org/doi/10.1098/rsob.240151
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!