Zebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosides.
Parkinson's disease is a neurodegenerative disorder characterized by the prominent degeneration of dopaminergic (DA) neurons among other cell types. Here we report a first chemical screen of over 5,000 compounds in zebrafish, aimed at identifying small molecule modulators of DA neuron development or...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2012-01-01
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| Serija: | PLoS ONE |
| Online dostop: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0035645&type=printable |
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