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Disruption of LRRK2 does not cause specific loss of dopaminergic neurons in zebrafish.

Mutations in LRRK2 are genetically linked to Parkinson's disease (PD) but its normal biological function is largely unknown. Sheng et al. recently reported that deletion of the WD40 domain of LRRK2 in zebrafish specifically causes PD-like loss of neurons and behavior defect. However, our similar ear...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guiqi Ren, Shengchang Xin, Song Li, Hanbing Zhong, Shuo Lin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2011-01-01
Saila:PLoS ONE
Sarrera elektronikoa:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0020263&type=printable
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