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A unique HMG-box domain of mouse Maelstrom binds structured RNA but not double stranded DNA.

Piwi-interacting piRNAs are a major and essential class of small RNAs in the animal germ cells with a prominent role in transposon control. Efficient piRNA biogenesis and function require a cohort of proteins conserved throughout the animal kingdom. Here we studied Maelstrom (MAEL), which is essenti...

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Detalles Bibliográficos
Principais autores: Pavol Genzor, Alex Bortvin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC4373776?pdf=render
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