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Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages

Abstract The continuous emergence of SARS-CoV-2 variants of concern has rendered many therapeutic monoclonal antibodies (mAbs) ineffective. To date, there are no clinically authorized therapeutic antibodies effective against the recently circulating Omicron sub-lineages BA.2.86 and JN.1. Here, we re...

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Hlavní autoři: Melanie R. Walker, Alexander Underwood, Kasper H. Björnsson, Sai Sundar Rajan Raghavan, Maria R. Bassi, Alekxander Binderup, Long V. Pham, Santseharay Ramirez, Mette Pinholt, Robert Dagil, Anne S. Knudsen, Manja Idorn, Max Soegaard, Kaituo Wang, Andrew B. Ward, Ali Salanti, Jens Bukh, Lea Barfod
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-10-01
Edice:Communications Biology
On-line přístup:https://doi.org/10.1038/s42003-024-06951-7
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